1Associate Prof.& HOD,Agadtantra Depatt. GAC,JABalpur
Abstract:
Since Vedic Period Prameha
(asrava) & its different types especially Madhumeha (Diabetes Mellitus) as
a life style disorder are disturbing the human era. Plants and plant extracts
were used to combat the disease as early as 1550 B.C. with as many as 400
"prescribed" before the development earlier this century of effective
medications to control diabetes. In this paper an attempt has been made to give
an overview of certain Indian plants with their phyto-constituents and
mechanism of action which have been studied for their antidiabetic activity.
Ayurveda describes number of plants used as herbal drugs play an important role
as alternative medicine due to less side effects and low cost. The active
principles present in medicinal plants have been reported to possess pancreatic
beta cells regenerating. insulin releasing effects and fighting the problem of
insulin resistance. Herbal drugs viz. Vijaysara, Haridra, Rasone, Yava, Amalak.
Azadirachta-indica, Momordica charantia, Aegle marmelos etc. are accepted &
claimed in Ayurveda for cure of Madhumeha.
Keywords-Last Asrava. Vijayasar, Diabetes Mellitus,
Introduction:
Madhu meha (a type of
Prameha) which has been correlated with Diabetes
Mellitus has become a global problem in spite of advances in modern science.
India has been projected by WHO as the country with the fastest growing
population of Diabetic patients. The ancient Indian physicians described not
only the sweetness of urine as one of the major symptoms but also the
relationship of the disease with disturbance of the 5 sheaths of the body
annamaya kasha (Food sheath), pranamaya kosha {Energy sheath), manomaya kosha
(Mind Sheath), vijnana maya kasha (Intellectual Sheath) and anandamaya kosha
(Bliss Sheath).
All classical texts describe Prameha. The word
Prameha derived from the root mih sechane means watering that means dilution of
everything in the body not only urine.The statement rightly said in Ayurvedic
literature since the Vedic period & the American Diabetes Association's
Standards of Medical Care in Diabetes presently states that:"Diabetes is a
chronic illness that requires continuing medical care & on-going patient
selfmanagement education & support to prevent acute complications & to
reduce the risk of long-term complications. Diabetes care is complex and
requires that many issues, beyond glycemic control, be addressed."
Discussion –
Recently,
medicinal plants and its derivatives have been used as an alternative to
allopathic medicine in many countries as appropriate hypoglycemic agents.
Either as a nutrient or as a source of food these herbs are being consumed by
the patient as well as healthy person.
The vast majority of cases of Diabetes fall into two
broad etiopathogenic categories. In one category, type I Diabetes, the cause is
an absolute deficiency of insulin secretion. In the other, much more prevalent
category, type 2 Diabetes, the cause is a combination of resistance to insulin
action and an inadequate compensatory insulin-secretary response. In
Diabetes, hyperglycemia generates reactive oxygen
species (ROS), which in turn cause lipid per oxidation and membrane damage and
these free radicals play an important role in the production of secondary
complications in Dabetes Mellitus (Kidney, Eye, Blood Vessel & Nerve
damage). Antioxidants have been shown to prevent the destruction of 8- cells by
inhibiting the each oxidation chain reaction and thus they may provide
protection against the development of Diabetes. Plants contain natural
antioxidants (Tannins, Flavonoids, and Vitamins C & E etc.) that can
preserve B- cell function and prevent diabetes induced ROS formation. In this
present review article an attempt was made to list out the herbal plants
possessing Antidiabetic activity by one or the other possible mechanisms.
Basis of Madhumeha (Diabetes Mellitus) treatment:
1. Patient education concerning the disease
2. Physical exercise
3.Diet
&
4.Hypoglycemic
agents
Sansaman Chikitsa according to Ayurvedic
texts-
Some
of the home and herbal remedies prescribed by Ayurveda are described below:-
1. Use drugs & foods having Tikta rasa.
2. Use Yava & Madhu together.
3. Amalki swaras with haridra & madhu.
4. Shilajit (1 Tula) along with Salsaradi Gana decoction.
5. Increase intake of vegetables like spinach,cucumber,
onion, sprouts, beans, garlic etc.
6. Refrain from taking stress.
7. Regular exercise. As per Susruta 100
Yojan a day.
Materials and Method:-
Various peer viewed journals and
Ayurvedic classical texts are critically analized and interpreted in making the
preventive & curative aspect of Madhumeha along with the herbal drugs &
their main phyto-constituents are aknowledged.
Conclusion: -
It is conclude that Madhumeha is a
disease of serious concern & Ayurvedic drugs are beneficial in treatment of
madhumeha separately & also in combination with other drugs.
References:-
1. Charak Samnita- Prameha nidan &
Prameha chikitsa
2. Susruta samhita-Madhumeha Nidan &
Chikitsa
3. www.carthjournals.org Volume 4 Issue
3, 2014
4.international journal ofphytotherapy research, ISSN 2278-5701
5.Diabetes Mellitus and as Herbal Treatment, Interrzational Journal of Research in Pharmaceutical and Biomedical Sciences ISSN: 2229-3701
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