Issue-32 Vol.1II, Jul.-Sep.2025 pp.60-64 Paper ID-E/D32/352
Agad Dravya Prayog in Prevention and Management of Cancer
Dr. Ravi
Kumar Srivastava1, Dr
Nidhi Srivastava2
1Associate
Prof.& HOD, Agadtantra
Depatt. GAC, JABalpur
2Associate
Prof. & HOD, Sharir
Rachana Deptt. GAC, Jabalpur
drraviksri2506@gmail.com
Abstract
Cancer
is a multifactorial disease characterized by uncontrolled cell proliferation
and genetic mutations. Ayurveda, under Agad Tantra, describes concepts of
Garavisha and Dooshivisha, which correspond to chronic toxin accumulation and
their systemic effects. These concepts provide a framework for understanding
carcinogenesis and for exploring detoxification (Shodhana) and rejuvenation
(Rasayana) therapies as preventive and therapeutic strategies. The present
study highlights the potential role of Agad Dravya in cancer prevention and
management through detoxification, immune modulation, and antioxidant
mechanisms.
Keywords-Agad
Tantra, Visha Dravya, Dooshivisha, Cancer, Detoxification, Ayurveda, Rasayana,
Immunity
सारांश
कैंसर एक बहु-कारक (multifactorial) रोग है, जिसकी विशेषता अनियंत्रित कोशिका वृद्धि और
आनुवंशिक उत्परिवर्तन (genetic mutations) है। आयुर्वेद में अगद
तंत्र के अंतर्गत गरविष और दूषीविष की संकल्पनाएँ वर्णित हैं, जो शरीर में दीर्घकालिक विष-संचयन और उसके तंत्रिकीय (systemic) प्रभावों से संबंधित हैं। ये अवधारणाएँ कैंसरोत्पत्ति (carcinogenesis)
को समझने तथा शोधन (detoxification) एवं रसायण
(rejuvenation) उपचारों को रोकथाम और चिकित्सा दोनों
दृष्टियों से परखने के लिए एक सैद्धांतिक आधार प्रदान करती हैं।
वर्तमान अध्ययन में अगद
द्रव्यों की संभावित भूमिका पर प्रकाश डाला गया है, जो शरीर
से विषहरण, प्रतिरक्षा-संशोधन (immune modulation) और प्रतिऑक्सीडेंट (antioxidant) क्रियाविधियों के
माध्यम से कैंसर की रोकथाम और प्रबंधन में सहायक हो सकते हैं।
मुख्य शब्द: अगद तंत्र, विष
द्रव्य, दूषीविष, कैंसर, शोधन, आयुर्वेद, रसायण,
प्रतिरक्षा
Introduction
Cancer
arises when normal cellular growth regulation mechanisms fail, leading to the
formation of tumors. Tumors may be benign or malignant, the latter being
capable of metastasis. Risk factors include genetic predisposition, chemical
exposure, poor diet, and lifestyle habits.
In
Ayurveda, chronic toxin accumulation (Dooshivisha) and improper metabolism of
Ama are viewed as major causes of diseases including Arbuda (tumor). The
correlation between chemical carcinogenesis and Visha exposure offers an
Ayurvedic understanding of cancer’s origin and progression.
Mechanism
of Carcinogenesis
Mutation and
inactivation of tumor suppressor genes
Uncontrolled cell
proliferation
Mutation in DNA repair
genes
Conversion of
proto-oncogenes into oncogenes
Inactivation of
multiple tumor suppressor genes
Development of
malignant growths
Ayurvedic
Perspective: Cancer as a Manifestation of Dooshivisha
Dooshivisha
refers to residual toxins that persist in the body due to incomplete
metabolism. These toxins gradually vitiate Doshas and Dhatus, leading to
pathological tissue proliferation analogous to cancer.
Acharya
Charaka mentions that when Dhatwagni is impaired by toxins, it causes abnormal
tissue growth—conceptually similar to tumorigenesis.
Modern
parallels include chronic exposure to environmental toxins, dietary
adulterants, and radiation, all contributing to genetic mutations and oxidative
stress.
Ayurvedic
Classification: Arbuda
According to Ayurvedic
texts:
Charaka Samhita:
Six types — Vataja, Pittaja, Kaphaja, Medohara, Siraja, and Mamsaja.
Sushruta Samhita:
Six types — Vataja, Pittaja, Kaphaja, Raktaja, Mamsaja, and Medoja.
Arbuda arises due to
vitiation of Doshas, obstruction of channels (Srotorodha), and abnormal tissue
proliferation (Mamsa Vriddhi).
Ayurvedic Therapeutic
Principles
Chikitsa Siddhanta:
Granthi and Vrana line
of treatment
Sadyovrana and
Shothahara management principles
Shodhana
(Purification), Shastra Karma (Surgical intervention), Lepa (Topical
applications)
Detoxification
Therapies:
Snehana (Oleation)
Swedana (Sudation)
Vamana (Emesis)
Virechana (Purgation)
Basti (Enema)
Raktamokshana
(Bloodletting)
Nasya and
Shirovirechana
Role
of Agada and Visha Dravya
Ayurvedic
formulations used in toxic disorders (Agad Yoga) show significant potential in
cancer management by detoxifying the body, neutralizing toxins, and enhancing
immunity.
Agada
Traditional Use
Dushivishari
Agada
Chronic toxin accumulation
Maha
Agada
Rapidly acting poisons
Ajit
Agada
Sthavara & Jangama poisons
Taksharya
Agada
Snake bite
Rishabh
Agada
Snake & insect poisons
Sanjeevan
Agada
Unconsciousness in poisoning
Shirishadi
Agada
General detoxification
Pharmacological
Evidence of Anti-Cancer Dravya
Dravya
Mechanism / Pharmacological Role
Haridra
(Turmeric)
Antioxidant, anti-inflammatory, antiviral, anti-cancer
Guduchi
(Tinospora cordifolia) Free radical scavenger, immune booster
Pippali
(Piper longum)
Induces apoptosis in colon cancer cells
Triphala
Antioxidant, anti-angiogenic, apoptosis inducer
Ashwagandha
(Withania somnifera) Anti-proliferative,
radioprotective
Brahma
Rasayana
Cellular rejuvenation, radioprotective
Tulsi
(Ocimum sanctum)
Antioxidant, immune modulator
Amla
(Emblica officinalis) Vitamin C source, DNA
protection
Role
of Detoxification and Rasayana Therapy
Neutralization:
Agadas neutralize toxins and prevent their chronic effects on Doshas and
Dhatus.
Rejuvenation: Rasayana therapies
restore cellular function and improve metabolism.
Immunity Boost: Enhanced immune
resistance reduces carcinogenic susceptibility.
Diet and Lifestyle
Ayurveda
recommends Satvik Ahara, regular Pranayama, meditation, and avoidance of toxic
food combinations (Viruddha Ahara) for prevention of carcinogenesis.
Conclusion
Ayurveda
provides a holistic model for cancer prevention and management through
detoxification, immune modulation, and rejuvenation. The Agad Tantra
principles, when integrated with modern oncology, offer novel pathways for
supportive cancer therapy and preventive care.
References
1-Charaka Samhita,
Nidana Sthana
2-Sushruta Samhita,
Sutra Sthana
3-Vagbhata, Ashtanga
Hridaya
4-Sharma PV, Dravyaguna
Vigyana
5-Singh
RH, Exploring Ayurveda in Integrative Oncology, AYU Journal (201
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